This Resident Evil 4 Remake guide page describes the fight with the final boss.

At the beginning of the fight you have to enter a small elevator.

The final boss of the game is Osmund Saddler.

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It will transform into a large mutated creature.

The magnum works best to weaken the enemy, although you have to shoot from a short distance.

There is a good chance that a single hit to the eye with a magnum bullet will destroy it.

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Explosive red barrelscan also help weaken the boss - detonate them after Saddler get close to them.

After destroying several eyes, theboss should collapse onto the arena.

You must then quickly run up to him andshove the knife into Saddler’s central eye.

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you’re free to climb to higher ledges and jump down to lower ones.

He may spit a poisonous substance- hide behind covers or quickly run to the side.

Boss can summon flying creatures to help him in the fight.

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If the flying monster catches Leon, use a knife to quickly to free yourself.

Only thenwill Saddler fall from the arena, and you will advance to the second phase of the battle.

  1. Vertical strikes- Run to the sides to avoid the boss' hit.

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Shoot thecore of the bosswith any weapon and dodge his attacks.

After a short time,Ada will appearand toss you aRocket Launcher Special.

You have to pick it up quickly.

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Launch a rocket at the core of the boss.

Hitting him will lead to defeating Saddler and winning the entire battle.

You’ll receive a gold trophyYou’re Small Time!

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Resident Evil 4