From this RE 4 Remake guide page you will learn more about upgrading your weapons.

To deal with them more efficiently, you must learn toupgrade your equipment.

Where to upgrade weapons?

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You will find him in many places on the map, usually appearing before or after more challenging fights.

Interact with the man and select theTune Uptab.

What is needed to upgrade weapons?

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The cost increases with subsequent upgrades.

It takesa lot of moneyto upgrade a weapon to its maximum value.

What to improve first?

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Usually, weapons can be upgraded in several ways.

As for the knife, you will see theDurabilityoption.

Upgrading this stat will make the knifedeteriorate much slower.

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On the other hand, if the knife is moredurable,you will strengthen your defense, e.g.

by being able to parry more often.

These are usually additional sights or recoil stabilizers.

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Resident Evil 4